Gore-Tex is a kind of fabric designed as an isolation material for clothes and shoes. In this example of a Gore-Tex boot, we can see how this five layers interact, protecting the feet from humidity and water. All of them are transpirable layers, this way the water vapour, as our sweat, can go out of the shoe, and the rain and puddle´s water stay outside of the boot. The three fisrt layers keep the water outside the boot. The most interior ones, keep the foot warm and with no humidity.
It is a perfect combination between transpiration and isolation,, which is reached through this kinds of materials.